It is well known that some forms of muscular dystrophies are caused by mutations in the genes coding for dystrophin and dysferlin – two proteins which both have important roles in the correct functioning of skeletal muscle.The dystrophin protein is located in the plasma membrane of skeletal muscle, and is an integral part of the dystrophin-glycoprotein complex (DGC). The DGC forms a link between the sarcolemma (the muscle cell membrane) and the cytoskeleton thereby ensuring cell membrane stability...